Caminero, 23, launched one off the catwalk during the bottom of the fourth inning off starting pitcher Erick Fedde.
The two-time All-Star went into Friday's match with 65 RBI and a .280/.369/.541 slash line (.911 OPS). He now needs 16 more home runs to set a new single-season high and 45 more RBI.
Tampa (64-44) are in the midst of an American League East pennant race with the New York Yankees (62-48) and currently possess the third-best record in all of baseball.