Sauerbrunn is one of several injured American players to miss the tournament, which kicks off on July 20th in Australia and New Zealand, after attacker Mallory Swanson went down with a knee injury in April.
Midfield stalwarts Sam Mewis and Catarina Macario are also sidelined for the holders.
Sauerbrunn is one of the USA's longest-standing players with 216 international appearances. She helped the Americans to two World Cup titles in 2015 and 2019. Her last international appearance was a friendly against Ireland in April.
Head coach Vlatko Andonovski is set to announce his 23-player squad imminently and reports said he informed players on Thursday of whether he planned to include them.