Kean, who has earned 17 international caps, played the full game on Sunday when Fiorentina beat AC Milan 2-1 in the Serie A.
Lucca received his first Italy call-up in March but had to withdraw due to a thigh injury. He has scored three goals in seven league appearances for Udinese this season.
Italy, top of Group two in Nations League after winning both their matches last month, will host Belgium on Oct. 10 and Israel on October 14.